Your whole study, live.
Centralive integrates everything a digital health study needs: wearables, questionnaires and EMAs, a drag-and-drop Participant App and just-in-time adaptive interventions that close the loop.
Used by research teams at
Design, collect, monitor, decide, intervene, optimize.
One connected workflow, from protocol to analysis-ready data.
- DesignBuild questionnaires, EMAs, schedules, reminders, the Participant App and its rules, with micro-randomization built in.
- CollectWearable data, smartphone sensing, questionnaire answers and EMAs arrive in one timeline.
- MonitorTrack adherence, act on alerts and export data for analysis.
- DecideRules check each participant at the decision points you set.
- InterveneNudges, questionnaires, EMAs, content or a Livi conversation reach the participant.
- OptimizeOutcomes from every decision show which interventions work, so you refine the pool and rules as the study runs.
Build your own Participant App with drag and drop.
One native iOS and Android app runs every study, designed by the people who wrote the protocol.
Drag a block onto the phone, or tap it to add.
From state to outcome, at every decision point.
A closed loop: data comes in, the right intervention goes out, and every decision is measured.
Data sources: what feeds each decision
Rule-based
IF/THEN decisions personalized from each participant’s Dynamic Profile, with a full decision log.
Advanced designs
Micro-randomized trials (MRTs), timing optimization and burden caps for intervention research.
Replace the patchwork.
| Today | With Centralive |
|---|---|
| A survey tool, separate case report forms, wearable exports, reminder scripts and spreadsheets | Questionnaires, EMAs, case report forms, devices, reminders and data in one place |
| One fixed intervention for every participant, decided before the study starts | A pool of interventions, matched to each participant's data and optimized as the study runs |
| A custom app costs far more and takes months to build, or a fixed layout you can't change | Your own Participant App, built with drag and drop in minutes |
| Adherence checked by hand across tools, often after data is already lost | Live adherence monitoring of everything in one Researcher Dashboard |
Bring the wearables and phones your study needs.
- Device stops syncing → the participant gets a reminder
- The gap continues → your team gets an alert
Smartphone sensing. Passive data from iPhone (Apple SensorKit) and Android phones, with a custom study app built for your study.
See the device library → About smartphone sensing →Personalized to every participant.
Each participant’s Dynamic Profile keeps their live context in one place. It updates as wearable, questionnaire and EMA data arrive, so your rules and interventions adapt to the person.
Live participant context
Each participant's current data, in one place.
Updates from data
Values refresh as wearable, questionnaire and EMA data arrive.
Group participants
Group participants by what their data shows.
Rules without code
Use profile values in JITAI rules and personalize thresholds.
Livi: AI agents for digital interventions.
Centralive connects with Livi so your interventions can be a two-way conversation, not only a pushed message. Livi agents are built from your own guidelines, connected to your study’s data, and governed by your rules.
IF steps < 200 by 14:00
THEN start a Livi conversation- KnowledgeYour protocol and guidelines✓
- ContextSleep 5.1 h · 140 steps · stress 7/10✓
- GuardrailsTone · escalation · PHI redaction✓
- GoalFind the barrier, agree one small step✓
You're at 140 steps. What's in the way today?
Back-to-back calls
Try a 5-minute walk after your next call?Your activity protocol · p. 4
OK, after the 3pm one
Logged as outcomeWhat researchers say.
Centralive gave me direct access to raw wearable sensor data, which significantly accelerated my pain assessment studies and opened up new possibilities for analysis.
Centralive’s multi-device integration enabled my team and I to test the use of Garmin wearables in a proof-of-concept study of live classical music. Centralive was able to include continuous HRV, sleep data and patient-reported outcomes in a single dataset. The biosignal processing and analytics of Centralive’s experts turned those signals into results we could interpret clinically, convincing us to move ahead with a pilot study.
Building a living learning lab that allows for the development of agentic population health interventions in a HIPAA compliant, safe and private platform is a steep climb but Centralive delivers all this and more. … Its safety monitoring, guardrails, and adherence tracking safely empowers teens on their own health journey.
With Centralive, I could integrate my tools smoothly and track adherence in real time, which allowed me to push my pregnancy health research forward faster than I imagined.
Centralive allowed me to bring wearable devices directly into my community-focused study, making it possible to explore how real-time physiological monitoring could be accepted and used by women aging with HIV.
Centralive provides the infrastructure we need to capture continuous heart rate, respiratory rate, stress, movement, and sleep alongside real-time reports of mental health symptoms, all within one platform.
Built by researchers, for researchers.
Centralive grew out of ZotCare at the UC Irvine Institute for Future Health.
Built for HIPAA, ready for international studies.
Designed around the HIPAA Security Rule’s technical safeguards, with the documentation your IRB and procurement office ask for.
- IRB Approval Made Easy
- eConsent Enabled
- Study Randomization
HIPAACompliant with HIPAA privacy and security standards
UK GDPRCompliant with UK GDPR standards
EU GDPRCompliant with EU GDPR regulations
Australian Privacy PrinciplesCompliant with the Australian Privacy Principles
Data Privacy FrameworkCertified for secure international data transfers (EU-U.S., UK & Swiss)
Encrypted everywhere
Data is encrypted in transit and at rest on HIPAA-eligible cloud infrastructure covered by BAAs.
Audit trail
A record of access to health data and of security-relevant actions.
International privacy
GDPR and UK GDPR, with regional data storage options.