NIH NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation (PAR-25-188)

NIH NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation (PAR-25-188)

The National Institute of Dental and Craniofacial Research (NIDCR) has announced the reissuance of PAR-25-188, a funding opportunity focused on advancing behavioral and social interventions. This phased cooperative agreement (UG3/UH3) is designed to facilitate the transition from rigorous clinical trial planning to full-scale implementation. The initiative prioritizes research that addresses the complex biopsychosocial factors influencing oral health and its comorbidities.

Scope

The scope of this funding opportunity encompasses a wide array of intervention research. NIDCR encourages applications that utilize novel methods such as mobile health (mHealth), artificial intelligence, and telehealth to expand the reach and effectiveness of oral health services. Projects must progress through an initial planning phase (UG3) characterized by milestone achievement before transitioning to the implementation phase (UH3). This structure ensures that only the most feasible and scientifically sound trials proceed to full execution. As highlighted in established implementation science literature, the use of theoretical frameworks like the Consolidated Framework for Implementation Research (CFIR) is critical for identifying modifiable factors that promote the adoption and maintenance of these interventions (Damschroder et al., 2009).

Eligibility

Eligible applicants include a broad spectrum of organizations, such as:

  • Public and private institutions of higher education.
  • Nonprofits with or without 501(c)(3) status.
  • For-profit organizations and small businesses.
  • State, local, and tribal government agencies.

Partnership

Collaborative and multi-disciplinary teams are highly encouraged. Successful applications often demonstrate strong partnerships between academic researchers, clinical practitioners, and community stakeholders. The inclusion of diverse perspectives is vital for ensuring that interventions are culturally appropriate and sustainable within real-world health systems, reflecting the core principles of the RE-AIM framework (Glasgow et al., 1999).

More info : https://grants.nih.gov/grants/guide/pa-files/PAR-25-188.html

Deadlines: Standard NIH due dates apply: The final expiration date for this announcement is January 7, 2028.


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